On Motif Statistics in Protein Spatial Networks

In Silico Analysis of Primary Sequence and Tertiary Structure of Lepidium Draba Peroxidase

Peroxidase enzymes are vastly applicable in industry and diagnosiss. Recently, we introduced a new kind of peroxidase gene from Lepidium draba (LDP). According to protein multiple sequence alignment results, LDP had 93% similarity and 88.96% identity with horseradish peroxidase C1A (HRP C1A). In the current study we employed in silico tools to determine, to which group of peroxidase enzymes LDP...

CpG Motif as an Adjuvant in Immunization of a Recombinant Plasmid Encoding Hepatitis C Virus Core Protein

Expression Analysis of RNA-Binding Motif Gene on Y Chromosome (RBMY) Protein Isoforms in Testis Tissue and a Testicular Germ Cell Cancer-Derived Cell Line (NT2)

a key factor in spermatogenesis and disorders associated with this protein have been recognized to be related to male infertility. Although it was suggested that this protein could have different functions during germ cell development, no studies have been conducted to uncover the mechanism of this potential function yet. Here, we analyzed the expression pattern of RBMY protein isoforms in test...

Predicting SUMOylation Sites

Recent evidence suggests that SUMOylation of proteins plays a key regulatory role in the assembly and dis-assembly of nuclear subcompartments, and may repress transcription by modifying chromatin. Determining whether a protein contains a SUMOylation site or not thus provides essential clues about a substrate’s intra-nuclear spatial association and function. Previous SUMOylation predictors are l...

Minfer: Inferring Motif Statistics From Sampled Edges

Characterizing motif (i.e., locally connected subgraph patterns) statistics is important for understanding complex networks such as online social networks and communication networks. Previous work made the strong assumption that the graph topology of interest is known, and that the dataset either fits into main memory or is stored on disk such that it is not expensive to obtain all neighbors of...